Comparative Accuracy and Data Differences

In-lab polysomnography (PSG) remains the “gold standard” for sleep apnea diagnosis because it tracks a significantly wider range of physiological data, including brain waves (EEG) and muscle activity. While the Alice NightOne (ANO) is highly sensitive for detecting obstructive sleep apnea (OSA), it has key differences in how it measures and reports data compared to in-lab studies.
»PubMed Central (PMC)(.gov)+3

Total Sleep Time (TST): Unlike in-lab PSG, the Alice NightOne does not measure brain waves, so it cannot distinguish between being awake and asleep. It uses “Monitoring Time” (MT) as a proxy, which is typically about 100 minutes longer than actual sleep time measured in a lab.

Severity Underestimation: Because the NightOne averages respiratory events over the entire monitoring period rather than just actual sleep time, its Respiratory Event Index (REI) is consistently lower than the in-lab Apnea-Hypopnea Index (AHI).

Average difference: Research shows a mean difference of about -8.0 evens/h compared to lab results.

Success Rate: Technical failures are more frequent at home (about 10.3%) compared to in-lab (only 0.4%) because lab staff are present to fix loose sensors in real-time. »PubMed Central (PMC)(.gov)+5

Summary of Diagnostic performance

Metric

Sensitiviy
(General OSA)

Specificity
(General OSA)

Accuracy
(at REI/AHI)

Scope of
Disorders